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Cord Blood Stem Cell Transplant – A Feasible Leukemia Treatment Choice

Posted In Blood Cancer, News on June 22, 2010 One Comment


Adult leukemia cases are faring reasonably well following stem cell transplant used from cord blood banking as they did when taken from ably-suited grown-up donor types, according to study investigators from United States.

The study authors claim that umbilical cord blood transplant procedure is a workable alternative in adult leukemia cases with urgent requirement for bone marrow transplantation to reinstate cells obliterated as a result of chemo or radiation therapies, however often failing to locate a donor.

Helming the study, Dr. Mary Eapen from the Medical College of Wisconsin explicates how their study finding pointed towards outlook of leukemia free existence being analogous irrespective of whether transplant was done from an umbilical cord blood unit or adult donors.

Stem cell transplantDuring a telephonic talk, Dr. Eapen stated that cord blood functioned despite not being a perfect match. Merely around one-half of all Caucasian adult patients were able to track an apt donor and the chances appear to diminish even more in case the ethnicity was Afro-American or Asian. She added that generally when there is no suitable tissue matching with a donor then the odds of experiencing a complication are elevated and it could lead to fatality. However, that risk appears to be lesser in case of stem cells drawn from the umbilical cord blood. The body is observed to have greater tolerance to cells from the placenta blood, in spite of not having a totally ideal match.

During the study which has been published in the journal Lancer Oncology, Dr. Eapen and associates did a comprehensive analysis of data taken from over two hundred transplant clinics across the globe. They did a comparison of the outcomes of 165 study entrants in the ages of sixteen years or more, having chronic leukemia that were given cord blood stem cell transplant against 888 grownups that were offered disparate stem cell transplantations and 472 patients that were offered separate bone marrow from donors.

Subsequent to 2 years, every one of the patients from these sets had an equal likelihood of surviving and being disease-free irrespective of the grafting source.

Dr. Eapen stated that the best part about umbilical cord blood stem cell transplant is that it could be employed for transplant cases that are not an ideal match and yet capable of arriving at a satisfactory ending, that is a disease-free existence.

Speaking in detail, Dr. Eapen stated that majority of the transplants being conducted employing cord blood are from public cord blood banks where the parents have done blood donation from their baby’s umbilical cord. The blood donated then undergoes stringent tests for ensuring the cell safety and well preservation.

She spoke about how several privately run cord blood banks classically do collection and storage of cord blood for personal usage by individuals or kin members.

This study analysis is bound to boost endeavours at increasing contributions to publicly run cord blood banks, especially by minority types that face the maximum difficulty locating a matching donor.

A public cord blood bank would provide coverage incurred during collection, testing and storing umbilical cord blood.


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One Comment »

  • Erika says:
    July 12, 2010 at 12:03 am

    Umbilical cord blood is a rich source of stem cells for transplantation, like bone marrow and peripheral blood..

    Treatment of cancer with very high-dose chemotherapy or radiation therapy may result in severe injury to blood-forming cells in marrow, the spongy material inside the center of bones..

    Reply to this comment »

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